A study suggests that lack of sleep prevents the brain from acclimatizing to threatening environments, potentially contributing to chronic anxiety.

Key facts
- •A study of 54 adults found that sleep-deprived individuals failed to acclimatize to threatening virtual environments.
- •Previous research indicated that emotional brain centers are over 60 percent more active after 35 hours of wakefulness.
- •Participants with higher heart rate variability reported less anxiety during the virtual reality test despite physiological stress markers.
- •Chronic hypervigilance resulting from sleep loss may manifest as pathological anxiety.
- •About one-third of adults in the West experience sleep problems at least once a week.
Researchers have found that sleep-deprived individuals struggle to adapt to threatening situations, remaining in a state of hypervigilance. While well-rested people show reduced stress after repeated exposure to unsettling environments, those who lack sleep maintain high stress levels. This inability to acclimatize may explain why sleep loss is linked to the development and persistence of anxiety disorders.
By the numbers
Virtual reality study methodology
Emma Sullivan at the University of Melbourne and her colleagues studied 54 healthy adults aged 18 to 30. Half of the participants stayed awake overnight, while the others slept for 8 hours in a lab. The following morning, all participants navigated an immersive virtual world that transitioned from a bright office to a dark, unsettling basement filled with ominous sounds.
Stress responses and heart health
Researchers monitored heart rates and skin-conductance levels to track fight-or-flight responses. While all participants initially showed stress, only the well-rested group demonstrated a reduction in stress upon re-entering the threatening space. The study also noted that participants with greater heart rate variability reported feeling less anxious during the experience, suggesting that factors improving heart health may help mitigate the effects of sleep loss.
Potential interventions
Experts suggest that addressing sleep issues can help manage anxiety, as the two conditions often exacerbate one another. Potential interventions include cognitive behavioural therapy, moderate-to-vigorous exercise to improve heart rate variability, and the use of naps or scheduled recovery sleep for those who cannot avoid sleep deprivation, such as shift workers.
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This article was independently rewritten by ManyPress editorial AI from reporting originally published by New Scientist.

