Dermatologists explain the benefits of niacinamide, a form of vitamin B3, and highlight recommended serums for various skin concerns.

Key facts
- •Niacinamide is a water-soluble form of vitamin B3 that functions as an antioxidant.
- •The ingredient helps reduce inflammation-induced collagen degradation and stimulates dermal fibroblasts.
- •Dermatologists recommend patch testing because niacinamide can be a common sensitizer for those with allergies.
- •Higher concentrations of 10% or more are available but may cause irritation for some users.
- •Niacinamide is compatible with various other skincare ingredients, including retinol, vitamin C, and AHAs.
Niacinamide, a water-soluble form of vitamin B3, is widely recognized by dermatologists as a versatile antioxidant that supports skin health. Experts note that the ingredient is particularly effective for treating acne, rosacea, and pigmentation while helping to regulate oil production and improve collagen levels. Because it can act as a sensitizer, dermatologists recommend patch testing before incorporating it into a daily routine.
Understanding Niacinamide Concentrations
According to dermatologist Dhaval Bhanusali, the concentration of niacinamide determines its primary function. Formulas containing 1% to 2% are typically used to calm the skin and support the barrier, while 5% to 6% concentrations are often used to address hyperpigmentation, fine lines, and skin texture. Concentrations of 6% to 10% or higher are available but are recommended less frequently due to the potential for skin irritation.
Expert-Recommended Serums
The selection of serums includes The Ordinary’s niacinamide and zinc formula, noted for its affordability and suitability for oily skin. Other recommendations include La Roche-Posay’s serum, which pairs niacinamide with Melasyl to target dark spots, and SkinCeuticals’s formula, which combines niacinamide with tranexamic and kojic acids. Additional highlighted products include Medik8’s Niacinamide Peptides, Anua’s brightening serum, Eadem’s vitamin C-infused formula for melanin-rich skin, and Arencia’s concentrated serum-cream.
Usage and Compatibility
Niacinamide is considered a versatile ingredient that pairs well with many other actives, including vitamin C, retinol, AHAs, and skin-lightening agents like azelaic acid. Dermatologists emphasize that it is suitable for most skin types, including those prone to acne. When selecting a product, experts advise looking for lightweight, quick-absorbing textures that do not pill or leave residue.
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This article was independently rewritten by ManyPress editorial AI from reporting originally published by Vogue.


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